značajno

1. significantly; considerably
   Cene su značajno porasle ove godine. — Prices have risen significantly this year.
   Novi lek je značajno smanjio bolove. — The new medicine significantly reduced the pain.
2. (of a look, gesture) meaningfully; knowingly
   Značajno me je pogledala i ćutala. — She gave me a meaningful look and said nothing.